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Publications

2016

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Frederick DW, Loro E, Liu L, Davila A Jr, Chellappa K, Silverman IM, Quinn WJ 3rd, Gosai SJ, Tichy ED, Davis JG, Mourkioti F, Gregory BD, Dellinger RW, Redpath P, Migaud ME, Nakamaru-Ogiso E, Rabinowitz JD, Khurana TS, Baur JA. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metabolism. 2016 Aug 9;24(2):269-82. PMID: 27508874.

 

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2014

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Cosgrove, BD., Gilbert, PM., Porpiglia, E., Mourkioti, F., Lee, SP., Corbel S.Y., Liewellyn, M.E., Delp, SL., Blau H.M. (2014) Rejuvenation of the aged muscle stem cell population restores strength to injured aged muscles. Nature Medicine, 20(3):255-64. Epub Feb 162014. PMID: 24531378.

  • This paper was highlighted in Nature Medicine under “News and Views” section: (2014) Rejuvenating aged muscle stem cells. Nature Medicine, 20:234-235.

 

 

2013

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Mourkioti, F., Kustan, J., Kraft, P., Way, JW., Zhao, MM., Kost-Alimova, M., Protopopov, A., DePinho, R., Bernstein, D., Meeker, AK., Blau, HM. (2013) Role of Telomere Dysfunction in Cardiac Failure in Duchenne Muscular Dystrophy. Nature Cell Biology, 15(8):895-904.

  • This paper was highlighted in Nature under “Research Highlights: Disease Research” section: (2013) Short Telomeres Damage Heart. Nature, 499:129.

 

 

2010

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Sacco, A*., Mourkioti, F*., Tran, R., Choi, J., Llewellyn, M., Kraft, P., Shkreli, M., Delp , S., Pomerantz, JH., Artandi, SE., Blau HM. (2010) Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice. Cell, 143(7):1059-71. Epub 2010 Dec 9. *Authors contributed equally.

  • This paper was highlighted in Cell under “Previews” section: Chamberlain, J.S. (2010) Duchenne Muscular Dystrophy Models Show Their Age. Cell, 143(7):1040-2.

 

Kratsios, P., Catela, C., Salimova, E., Huth, M., Berno, V., Rosenthal, N., and Mourkioti, F. (2010) Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. Circ. Res.,106(3):559-72. Epub 2009 Dec 10.

 

Kratsios, P., Huth, M., Temmerman, L., Salimova, E., Al Banchaabouchi, M., Sgoifo, A., Manghi, M., Suzuki, K., Rosenthal, N., and Mourkioti, F**. (2010) Antioxidant amelioration of dilated cardiomyopathy caused by conditional deletion of NEMO/IKKg in cardiomyocytes. Circ Res., 106(1):133-44. Epub 2009 Oct. 22. ** corresponding author.

  • This paper was highlighted in Circulation Research under “Editorials” section: Nemchenko, A., Hill, J.A. (2010) NEMO nuances NF-kappaB. Circ. Res. 106(1):10-2.

 

 

2009

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Ruffel, D*., Mourkioti, F.*, Gambardella, A.*, Kirstetter, P., Lopez, R.G., Rosenthal, N. and Nerlov, C. (2009) A CREB-C/EBPb cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair. Proc Natl Acad Sci USA 106(41): 17475-80 *Authors contributed equally.

 

 

2008

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Mourkioti, F., Slonimsky, E., Huth, M., Berno, V., and Rosenthal, N. (2008) Analysis of CRE-mediated recombination driven by myosin light chain 1/3 regulatory elements in embryonic and adult skeletal muscle: a tool to study fiber specification. Genesis 46(8):424-30.

 

Mourkioti, F.** and Rosenthal, N. (2008) NF-kB signaling in skeletal muscle: prospects for intervention in muscle diseases. Journal of Molecular Medicine 86(7):747-59. ** corresponding author.

 

 

2007

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Lara-Pezzi, E., Paul, A., McCullagh, K., Winn, N., Slonimsky, E., Santini, M.P., Mourkioti, F., Fukushima, S., Suzuki, K., and Rosenthal, N. (2007) A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration. Journal of Cell Biology 179(6):1205-18.

 

2006

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Mourkioti, F.**, Kratsios, P., Luedde, T., Adami, R., Parente, V., Bottinelli, R., Song, Y., Delafontaine, P., Pasparakis, M., and Rosenthal, N. (2006) Targeted ablation of IKK2 increases skeletal muscle strength, counters atrophy and promotes regeneration. Journal of Clinical Investigation 116(11): 2945-2954. **corresponding author. (Cover).

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

  • This paper was highlighted in Journal of Clinical Investigation under “Commentaries” section: Karin, M. Role for IKK2 in muscle: waste not, want not. J. Clin. Invest. 116(11):2866-8.

 

 

2005

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Mourkioti, F. and Rosenthal, N. (2005) IGF-1, inflammation and stem cells: interactions during muscle regeneration. Trends Immunol. 26(10): 535-542.

 

 

2002

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Peter A, Schottler P, Werner M, Beinert N, Dowe G, Burkert P, Mourkioti F, Dentzer L, He Y, Deak P, Benos PV, Gatt MK, Murphy L, Harris D, Barrell B, Ferraz C, Vidal S, Brun C, Demaille J, Cadieu E, Dreano S, Gloux S, Lelaure V, Mottier S, Galibert F, Borkova D, Minana B, Kafatos FC, Bolshakov S, Siden-Kiamos I, Papagiannakis G, Spanos L, Louis C, Madueno E, de Pablos B, Modolell J, Bucheton A, Callister D, Campbell L, Henderson NS, McMillan PJ, Salles C, Tait E, Valenti P, Saunders RD, Billaud A, Pachter L, Klapper R, Janning W, Glover DM, Ashburner M, Bellen HJ, Jackle H, Schafer U. (2002) Mapping and identification of essential gene functions on the X chromosome of Drosophila. EMBO Rep. 3(1): 34-38.

 

 

2001

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Benos, P.V., Gatt, M.K., Murphy. L., Harris, D., Barrell, B., Ferraz, C., Vidal, S., Brun, C., Demaille, J., Cadieu, E., Dreano, S., Gloux, S., Lelaure, V., Mottier, S., Galibert ,F., Borkova, D., Minana, B., Kafatos, F.C., Bolshakov, S., Siden-Kiamos, I., Papagiannakis, G., Spanos, L., Louis, C., Madueno, E., de Pablos, B., Modolell, J., Peter, A., Schottler, P., Werner, M., Mourkioti, F., Beinert, N., Dowe, G., Schafer, U., Jackle, H., Bucheton, A., Callister, D., Campbell, L., Henderson, N.S., McMillan, P.J., Salles, C., Tait, E., Valenti, P., Saunders, R.D., Billaud, A., Pachter, L., Glover, D.M., and Ashburner, M. (2001) From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. Genome Res. 11(5): 710-730.

 

 

2000

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Benos, P.V., Gatt, M.K., Ashburner, M., Murphy, L., Harris, D., Barrell, B., Ferraz, C., Vidal, S., Brun, C., Demailles, J., Cadieu, E., Dreano, S., Gloux, S., Lelaure, V., Mottier, S., Galibert, F., Borkova, D., Minana, B., Kafatos, F.C., Louis, C., Siden-Kiamos, I., Bolshakov, S., Papagiannakis, G., Spanos, L., Cox, S., Madueno, E., de Pablos, B., Modolell, J., Peter, A., Schottler, P., Werner, M., Mourkioti, F., Beinert, N., Dowe, G., Schafer, U., Jackle, H., Bucheton, A., Callister, D.M., Campbell, L.A., Darlamitsou, A., Henderson, N.S., McMillan, P.J., Salles, C., Tait, E.A., Valenti, P., Saunder, R.D., and Glover, D.M. (2000) From sequence to chromosome: the tip of the X chromosome of D. melanogaster. Science 287(5461): 2220-2222.

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